Mapping the human heart one cell at a time
The 37 trillion cells of the human body have a remarkable array of specialised functions, and must cooperate and collaborate in time and space to construct a functioning human. Harnessing cutting edge single cell genomics, imaging and computational technologies, my lab has been attempting to understand this cellular diversity, how it is generated during development, and how it goes wrong in disease.
My talk will illustrate the relevance of cell atlasing to understand the cellular composition of the human heart, including new insights into its immune cells and the pacemaker cells of the sinoatrial node. In doing so I hope to illustrate the power of single cell approaches in unlocking fundamental knowledge about the human body.
The recorded seminar can be viewed here (CRC members login needed).